Repurposing Synthetic Congeners of a Natural Product Aurone Unveils a Lead Antitumor Agent Inhibiting Folded P-Loop Conformation of MET Receptor Tyrosine Kinase
A library of 24 congeners of the natural product sulfuretin were evaluated against nine panels representing nine cancer diseases. While sulfuretin elicited very weak activities at 10 µM concentration, congener <b>1t</b> was identified as a potential compound triggering growth inhibition...
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Main Authors: | , , , , , , , , , , , , |
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Format: | Book |
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MDPI AG,
2023-11-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |