Synthesis, Spatial Structure and Analgesic Activity of Sodium 3-Benzylaminocarbonyl-1-methyl-2,2-dioxo-1H-2λ6,1-benzothiazin-4-olate Solvates

• Главные авторы: Igor V. Ukrainets (Автор), Lidiya A. Petrushova (Автор), Svitlana V. Shishkina (Автор), Lina A. Grinevich (Автор), Galina Sim (Автор)
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• Опубликовано: MDPI AG, 2016-10-01T00:00:00Z.
• Предметы: article
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In order to obtain and then test pharmocologically any possible conformers of the new feasible analgesic N-benzyl-4-hydroxy-1-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide, its 4-O-sodium salt was synthesized using two methods. X-ray diffraction study made possible to determine that, dependi...