Synthesis, Spatial Structure and Analgesic Activity of Sodium 3-Benzylaminocarbonyl-1-methyl-2,2-dioxo-1H-2λ6,1-benzothiazin-4-olate Solvates

• 主要な著者: Igor V. Ukrainets (著者), Lidiya A. Petrushova (著者), Svitlana V. Shishkina (著者), Lina A. Grinevich (著者), Galina Sim (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2016-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In order to obtain and then test pharmocologically any possible conformers of the new feasible analgesic N-benzyl-4-hydroxy-1-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide, its 4-O-sodium salt was synthesized using two methods. X-ray diffraction study made possible to determine that, dependi...