New MraY_AA Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole

• मुख्य लेखकों: Hongwei Wan (लेखक), Raja Ben Othman (लेखक), Laurent Le Corre (लेखक), Mélanie Poinsot (लेखक), Martin Oliver (लेखक), Ana Amoroso (लेखक), Bernard Joris (लेखक), Thierry Touzé (लेखक), Rodolphe Auger (लेखक), Sandrine Calvet-Vitale (लेखक), Michaël Bosco (लेखक), Christine Gravier-Pelletier (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

New inhibitors of the bacterial transferase MraY from <i>Aquifex aeolicus</i> (MraY_AA), based on the aminoribosyl uridine central core of known natural MraY inhibitors, have been designed to generate interaction of their oxadiazole linker with the key amino acids (...