Myelin Basic Protein and a Multiple Sclerosis-related MBP-peptide Bind to Oligonucleotides

Aptamer ligands for myelin basic protein (MBP) were obtained using the systematic evolution of ligand by exponential enrichment (SELEX) method. Two clones were isolated from a pool of oligonucleotides and tested for MBP targeting. Using purified MBP, we demonstrated the binding activity of the aptam...

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Main Authors: Guido Tomás Rozenblum (Author), Tomás Kaufman (Author), Alfredo Daniel Vitullo (Author)
Format: Book
Published: Elsevier, 2014-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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