Myelin Basic Protein and a Multiple Sclerosis-related MBP-peptide Bind to Oligonucleotides

• मुख्य लेखकों: Guido Tomás Rozenblum (लेखक), Tomás Kaufman (लेखक), Alfredo Daniel Vitullo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2014-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Aptamer ligands for myelin basic protein (MBP) were obtained using the systematic evolution of ligand by exponential enrichment (SELEX) method. Two clones were isolated from a pool of oligonucleotides and tested for MBP targeting. Using purified MBP, we demonstrated the binding activity of the aptam...