Loading Dose of Ceftazidime Needs to Be Increased in Critically Ill Patients: A Retrospective Study to Evaluate Recommended Loading Dose with Pharmacokinetic Modelling

• Asıl Yazarlar: Manon Launay (Yazar), Edouard Ollier (Yazar), Benjamin Kably (Yazar), Félicien Le Louedec (Yazar), Guillaume Thiery (Yazar), Julien Lanoiselée (Yazar), Sophie Perinel-Ragey (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2024-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

To rapidly achieve ceftazidime target concentrations, a 2 g loading dose (LD) is recommended before continuous infusion, but its adequacy in critically ill patients, given their unique pharmacokinetics, needs investigation. This study included patients from six ICUs in Saint-Etienne and Paris, Franc...