Loading Dose of Ceftazidime Needs to Be Increased in Critically Ill Patients: A Retrospective Study to Evaluate Recommended Loading Dose with Pharmacokinetic Modelling

• Những tác giả chính: Manon Launay (Tác giả), Edouard Ollier (Tác giả), Benjamin Kably (Tác giả), Félicien Le Louedec (Tác giả), Guillaume Thiery (Tác giả), Julien Lanoiselée (Tác giả), Sophie Perinel-Ragey (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2024-08-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

To rapidly achieve ceftazidime target concentrations, a 2 g loading dose (LD) is recommended before continuous infusion, but its adequacy in critically ill patients, given their unique pharmacokinetics, needs investigation. This study included patients from six ICUs in Saint-Etienne and Paris, Franc...