CD38 Deficiency Promotes Inflammatory Response through Activating Sirt1/NF-κB-Mediated Inhibition of TLR2 Expression in Macrophages

• 主要な著者: Yisong Qian (著者), Chuqiao Chen (著者), Leliang Ma (著者), Ziwei Wang (著者), Ling-Fang Wang (著者), Li Zuo (著者), Yaqin Yang (著者), Xiang Huang (著者), Meixiu Jiang (著者), Xiaolei Wang (著者), Huidong Shi (著者), Mingui Fu (著者), Ke-Yu Deng (著者), Hong-Bo Xin (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2018-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

CD38 was first identified as a lymphocyte-specific antigen and then has been found to be widely expressed in a variety of cell types. The functions of CD38 are involved in numerous biological processes including immune responses. Here, we showed the downregulations of both TLR2 mRNA and protein in m...