Oridonin alleviates the inhibitory effect of lipopolysaccharide on the proliferation and osteogenic potential of periodontal ligament stem cells by inhibiting endoplasmic reticulum stress and NF-κB/NLRP3 inflammasome signaling
Abstract Background The aim of this study was to investigate the protective effect and mechanism of oridonin in an in vitro lipopolysaccharide (LPS)-induced human periodontal ligament stem cells (hPDLSCs) model of periodontitis. Methods Primary hPDLSCs were isolated and cultured, and then the expres...
Saved in:
Main Authors: | Junhao Jiang (Author), Nong Zhang (Author), Haibo Song (Author), Ya Yang (Author), Juan Li (Author), Xiaoli Hu (Author) |
---|---|
Format: | Book |
Published: |
BMC,
2023-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pinelliae rhizoma alleviated acute lung injury induced by lipopolysaccharide via suppressing endoplasmic reticulum stress-mediated NLRP3 inflammasome
by: Ning-ning Wang, et al.
Published: (2022) -
Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation
by: Tianyuan Ye, et al.
Published: (2018) -
Ox-LDL Causes Endothelial Cell Injury Through ASK1/NLRP3-Mediated Inflammasome Activation via Endoplasmic Reticulum Stress
by: Hang L, et al.
Published: (2020) -
The Impact of NLRP3 Inflammasome on Osteoblasts and Osteogenic Differentiation: A Literature Review
by: Yang Z, et al.
Published: (2024) -
TAZ reverses the inhibitory effects of LPS on the osteogenic differentiation of human periodontal ligament stem cells through the NF-κB signaling pathway
by: Shuyi Dong, et al.
Published: (2024)