Zonisamide Increases Dopamine Turnover in the Striatum of Mice and Common Marmosets Treated With MPTP

• Principais autores: Hayato Yabe (Autor), Mohammed Emamussalehin Choudhury (Autor), Madoka Kubo (Autor), Noriko Nishikawa (Autor), Masahiro Nagai (Autor), Masahiro Nomoto (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2009-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract.: The effect of zonisamide, an antiepileptic agent with anti-parkinsonian effects, was studied on dopamine neurons of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 mice and common marmosets. Groups of mice (n = 8 - 9) were treated with: MPTP (15 mg/kg every 2 h ×4); MPTP p...