Temperature Dependence of the Complexation Mechanism of Celecoxib and Hydroxyl-β-cyclodextrin in Aqueous Solution
Hydroxypropyl-β-cyclodextrin (HP-β-CD) is commonly used as a complexation reagent to solubilize compounds with poor aqueous solubility to improve in vivo dosing. However, the degree of solubility enhancement was often limited by the formation of only a 1:1 complex and a low complexation constant (K)...
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2014-08-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |