Involvement of Substance P and the Neurokinin-1 Receptor in Radiation-Induced Hair Loss in Mice

• 主要な著者: Kouichi Yamamoto (著者), Naoko Kureyama (著者), Keiko Asano (著者), Toshiji Ikeda (著者), Atsushi Yamatodani (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2010-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

We investigated the involvement of substance P (SP) and the neurokinin-1 receptor (NK1 R) in the development of radiation-induced hair loss in mice. A dose of 40 Gy of gamma irradiation induced hair loss from the 10th to at least the 60th day after irradiation. A specific NK1R antagonist, CP-99,994,...