Design and evaluation of nicorandil extended-release tablet

• Váldodahkkit: Ju-Young Kim (Dahkki), Chun-Woong Park (Dahkki), Beom-Jin Lee (Dahkki), Eun-Seok Park (Dahkki), Yun-Seok Rhee (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2015-04-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The aim of this study was to design and evaluate extended-release formulations of a model drug, nicorandil, in order to achieve the desired steady-state plasma concentration of drug in vivo. Simulation was employed to estimate optimum dissolution and absorption rate of nicorandil. The dissolution te...