Design and evaluation of nicorandil extended-release tablet

• Asıl Yazarlar: Ju-Young Kim (Yazar), Chun-Woong Park (Yazar), Beom-Jin Lee (Yazar), Eun-Seok Park (Yazar), Yun-Seok Rhee (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2015-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The aim of this study was to design and evaluate extended-release formulations of a model drug, nicorandil, in order to achieve the desired steady-state plasma concentration of drug in vivo. Simulation was employed to estimate optimum dissolution and absorption rate of nicorandil. The dissolution te...