Schisandrol A protects AGEs-induced neuronal cells death by allosterically targeting ATP6V0d1 subunit of V-ATPase

• Main Authors: Xiaoqing Zhou (Author), Shaoyang Zhao (Author), Tingting Liu (Author), Lu Yao (Author), Meimei Zhao (Author), Xiaoming Ye (Author), Xiaowen Zhang (Author), Qiang Guo (Author), Pengfei Tu (Author), Kewu Zeng (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes have been shown to cause progressive neuronal injury with pain and numbness via advanced glycation end-products (AGEs)-induced neuronal cell apoptosis; however, the valuable drug targets for diabetic neuropathy have been poorly reported so far. In this study, we discovered a natural small-m...