Schisandrol A protects AGEs-induced neuronal cells death by allosterically targeting ATP6V0d1 subunit of V-ATPase

• Glavni autori: Xiaoqing Zhou (Autor), Shaoyang Zhao (Autor), Tingting Liu (Autor), Lu Yao (Autor), Meimei Zhao (Autor), Xiaoming Ye (Autor), Xiaowen Zhang (Autor), Qiang Guo (Autor), Pengfei Tu (Autor), Kewu Zeng (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2022-10-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Diabetes have been shown to cause progressive neuronal injury with pain and numbness via advanced glycation end-products (AGEs)-induced neuronal cell apoptosis; however, the valuable drug targets for diabetic neuropathy have been poorly reported so far. In this study, we discovered a natural small-m...