Pathogenesis of the Metabolic Syndrome: Insights from Monogenic Disorders

• Principais autores: Rinki Murphy (Autor), Richard W. Carroll (Autor), Jeremy D. Krebs (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2013-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Identifying rare human metabolic disorders that result from a single-gene defect has not only enabled improved diagnostic and clinical management of such patients, but also has resulted in key biological insights into the pathophysiology of the increasingly prevalent metabolic syndrome. Insulin resi...