Pathogenesis of the Metabolic Syndrome: Insights from Monogenic Disorders

• Главные авторы: Rinki Murphy (Автор), Richard W. Carroll (Автор), Jeremy D. Krebs (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2013-01-01T00:00:00Z.
• Предметы: article
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Identifying rare human metabolic disorders that result from a single-gene defect has not only enabled improved diagnostic and clinical management of such patients, but also has resulted in key biological insights into the pathophysiology of the increasingly prevalent metabolic syndrome. Insulin resi...