Selective COX-2 Inhibitors: Road from Success to Controversy and the Quest for Repurposing

• मुख्य लेखकों: Afaf A. El-Malah (लेखक), Magdy M. Gineinah (लेखक), Pran Kishore Deb (लेखक), Ahdab N. Khayyat (लेखक), Monika Bansal (लेखक), Katharigatta N. Venugopala (लेखक), Anfal S. Aljahdali (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The introduction of selective COX-2 inhibitors (so-called 'coxibs') has demonstrated tremendous commercial success due to their claimed lower potential of serious gastrointestinal adverse effects than traditional NSAIDs. However, following the repeated questioning on safety concerns, the c...