Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors

• Главные авторы: Camila C. Bitencourt Brito (Автор), Hélder Vinicius Carneiro da Silva (Автор), Daci José Brondani (Автор), Antonio Rodolfo de Faria (Автор), Rafael Matos Ximenes (Автор), Ivanildo Mangueira da Silva (Автор), Julianna F. C. de Albuquerque (Автор), Marcelo Santos Castilho (Автор)
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• Опубликовано: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Leishmaniasis is considered as one of the major neglected tropical diseases due to its magnitude and wide geographic distribution. Leishmania braziliensis, responsible for cutaneous leishmaniasis, is the most prevalent species in Brazil. Superoxide dismutase (SOD) belongs to the antioxidant pathway...