Synthesis and biological evaluation of thiazole derivatives as LbSOD inhibitors

• Main Authors: Camila C. Bitencourt Brito (Author), Hélder Vinicius Carneiro da Silva (Author), Daci José Brondani (Author), Antonio Rodolfo de Faria (Author), Rafael Matos Ximenes (Author), Ivanildo Mangueira da Silva (Author), Julianna F. C. de Albuquerque (Author), Marcelo Santos Castilho (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmaniasis is considered as one of the major neglected tropical diseases due to its magnitude and wide geographic distribution. Leishmania braziliensis, responsible for cutaneous leishmaniasis, is the most prevalent species in Brazil. Superoxide dismutase (SOD) belongs to the antioxidant pathway...