Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells
Calcitriol, a vitamin D<sub>3</sub> metabolite, is approved for various indications because it is the bioactive form of vitamin D in the body. The purpose of this study was to predict the clinical significance of cytochrome P450 (CYP) induction by calcitriol using in vitro human cryopres...
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| Main Authors: | , , , , , |
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| Format: | Book |
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MDPI AG,
2021-01-01T00:00:00Z.
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