Diminished CD40L expression on T-cells in a case of disseminated cryptococcosis

• Egile Nagusiak: Supreet Kumar Mohanty (Egilea), Deepshi Thakral (Egilea), Devika Gupta (Egilea), Prabin Kumar (Egilea), Dipendra Kumar Mitra (Egilea)
• Formatua: Liburua
• Argitaratua: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

X-linked hyperimmunoglobulin M (HIGM) syndrome may increase the susceptibility of patients to disseminated cryptococcal infections primarily due to CD40L deficiency that causes defective cross talk between T- and B-cells, thus preventing class switching. In HIGM syndrome, serum IgM levels are elevat...