Pharmacokinetics, safety and tolerability of L-3-n-butylphthalide tablet after single and multiple oral administrations in healthy Chinese volunteers

• Glavni autori: Meng Wang (Autor), Quan-ying Zhang (Autor), Wen-yan Hua (Autor), Ming Huang (Autor), Wen-jia Zhou (Autor), Kun Lou (Autor), Yue-ying Peng (Autor)
• Format: Knjiga
• Izdano: Universidade de São Paulo, 2015-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

L-3-n-butylphthalide (L-NBP) is a naturally occurring antioxidant, which can be used for the treatment of acute ischemic stroke and vascular dementia. This study evaluated the safety, tolerability and pharmacokinetics of L-NBP tablets in healthy Chinese volunteers. This was a single-center, randomiz...