Pharmacokinetics, safety and tolerability of L-3-n-butylphthalide tablet after single and multiple oral administrations in healthy Chinese volunteers

• Main Authors: Meng Wang (Author), Quan-ying Zhang (Author), Wen-yan Hua (Author), Ming Huang (Author), Wen-jia Zhou (Author), Kun Lou (Author), Yue-ying Peng (Author)
• Format: Book
• Published: Universidade de São Paulo, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

L-3-n-butylphthalide (L-NBP) is a naturally occurring antioxidant, which can be used for the treatment of acute ischemic stroke and vascular dementia. This study evaluated the safety, tolerability and pharmacokinetics of L-NBP tablets in healthy Chinese volunteers. This was a single-center, randomiz...