RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells

• Main Authors: Hao Zhang (Author), Shenghua Zhang (Author), Hongwei He (Author), Caixia Zhang (Author), Yi Chen (Author), Dongke Yu (Author), Jianhua Chen (Author), Rongguang Shao (Author)
• Format: Book
• Published: Elsevier, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To increase the efficacy of currently used anti-cancer genotoxins, one of the current efforts is to find agents that can sensitize cancer cells to genotoxins so that the efficacious doses of genotoxins can be lowered to reduce deleterious side-effects. In this study, we reported that a synthetic Ras...