RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells

• Главные авторы: Hao Zhang (Автор), Shenghua Zhang (Автор), Hongwei He (Автор), Caixia Zhang (Автор), Yi Chen (Автор), Dongke Yu (Автор), Jianhua Chen (Автор), Rongguang Shao (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2014-04-01T00:00:00Z.
• Предметы: article
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To increase the efficacy of currently used anti-cancer genotoxins, one of the current efforts is to find agents that can sensitize cancer cells to genotoxins so that the efficacious doses of genotoxins can be lowered to reduce deleterious side-effects. In this study, we reported that a synthetic Ras...