The Serotonin Receptor 6 Antagonist Idalopirdine and Acetylcholinesterase Inhibitor Donepezil Have Synergistic Effects on Brain Activity-A Functional MRI Study in the Awake Rat
The 5-HT6 receptor is a promising target for cognitive disorders, in particular for Alzheimer's disease (AD) and other CNS disorders. The high-affinity and selective 5-HT6 receptor antagonist idalopirdine (Lu AE58054) is currently in development for mild-moderate AD as adjunct therapy to acetyl...
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| Main Authors: | , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2017-06-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |