The Serotonin Receptor 6 Antagonist Idalopirdine and Acetylcholinesterase Inhibitor Donepezil Have Synergistic Effects on Brain Activity-A Functional MRI Study in the Awake Rat

The 5-HT6 receptor is a promising target for cognitive disorders, in particular for Alzheimer's disease (AD) and other CNS disorders. The high-affinity and selective 5-HT6 receptor antagonist idalopirdine (Lu AE58054) is currently in development for mild-moderate AD as adjunct therapy to acetyl...

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Váldodahkkit: Craig F. Ferris (Dahkki), Praveen Kulkarni (Dahkki), Jason R. Yee (Dahkki), Mark Nedelman (Dahkki), Inge E. M. de Jong (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: Frontiers Media S.A., 2017-06-01T00:00:00Z.
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3rd Floor Main Library

oažžasuvvan: 3rd Floor Main Library
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