Spray-Dried Formulation of Epicertin, a Recombinant Cholera Toxin B Subunit Variant That Induces Mucosal Healing

• Κύριοι συγγραφείς: Micaela A. Reeves (Συγγραφέας), Joshua M. Royal (Συγγραφέας), David A. Morris (Συγγραφέας), Jessica M. Jurkiewicz (Συγγραφέας), Nobuyuki Matoba (Συγγραφέας), Krystal T. Hamorsky (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2021-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Epicertin (EPT) is a recombinant variant of the cholera toxin B subunit, modified with a C-terminal KDEL endoplasmic reticulum retention motif. EPT has therapeutic potential for ulcerative colitis treatment. Previously, orally administered EPT demonstrated colon epithelial repair activity in dextran...