Glucagon-to-insulin ratio is pivotal for splanchnic regulation of FGF-21 in humans

• Principais autores: Jakob Schiøler Hansen (Autor), Jens Otto Clemmesen (Autor), Niels Henry Secher (Autor), Miriam Hoene (Autor), Andrea Drescher (Autor), Cora Weigert (Autor), Bente Klarlund Pedersen (Autor), Peter Plomgaard (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2015-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background & aims: Fibroblast growth factor 21 (FGF-21) is a liver-derived metabolic regulator induced by energy deprivation. However, its regulation in humans is incompletely understood. We addressed the origin and regulation of FGF-21 secretion in humans. Methods: By determination of arterial-...