Cumulative Laxation Response with Methylnaltrexone: Implications for Hospitalized Patients with Advanced Illness and Opioid-Induced Constipation

• Главные авторы: David Farchadi, MD, MS (Автор), Neal E. Slatkin, MD (Автор), Nancy Stambler, DrPH (Автор), Robert J. Israel, MD (Автор), Michael Matus, MD (Автор)
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• Опубликовано: Elsevier, 2023-01-01T00:00:00Z.
• Предметы: article
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Background: Opioid-induced constipation (OIC) may increase the risk of fecal impaction and mortality in patients with advanced illness. Methylnaltrexone (MNTX) is efficacious for OIC. Objective: The purpose of this analysis was to evaluate cumulative rescue-free laxation response with repeat MNTX do...