Tubulin/microtubules as novel clozapine targets

• Príomhchruthaitheoirí: Mizuki Hino (Údar), Takeshi Kondo (Údar), Yasuto Kunii (Údar), Junya Matsumoto (Údar), Akira Wada (Údar), Shin‐ichi Niwa (Údar), Mitsutoshi Setou (Údar), Hirooki Yabe (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Wiley, 2022-03-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Abstract Aim Clozapine is currently the only effective drug for treatment‐resistant schizophrenia; nonetheless, its pharmacological mechanism remains unclear, and its administration is limited because of severe adverse effects. By comparing the binding proteins of clozapine and its derivative olanza...