A founder mutation in the <it>PEX6</it> gene is responsible for increased incidence of Zellweger syndrome in a French Canadian population

• Main Authors: Levesque Sebastien (Author), Morin Charles (Author), Guay Simon-Pierre (Author), Villeneuve Josee (Author), Marquis Pascale (Author), Yik Wing (Author), Jiralerspong Sarn (Author), Bouchard Luigi (Author), Steinberg Steven (Author), Hacia Joseph G (Author), Dewar Ken (Author), Braverman Nancy E (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Zellweger syndrome (ZS) is a peroxisome biogenesis disorder due to mutations in any one of 13 <it>PEX</it> genes. Increased incidence of ZS has been suspected in French-Canadians of the Saguenay-Lac-St-Jean region (SLSJ)...