A founder mutation in the <it>PEX6</it> gene is responsible for increased incidence of Zellweger syndrome in a French Canadian population

• Glavni autori: Levesque Sebastien (Autor), Morin Charles (Autor), Guay Simon-Pierre (Autor), Villeneuve Josee (Autor), Marquis Pascale (Autor), Yik Wing (Autor), Jiralerspong Sarn (Autor), Bouchard Luigi (Autor), Steinberg Steven (Autor), Hacia Joseph G (Autor), Dewar Ken (Autor), Braverman Nancy E (Autor)
• Format: Knjiga
• Izdano: BMC, 2012-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Zellweger syndrome (ZS) is a peroxisome biogenesis disorder due to mutations in any one of 13 <it>PEX</it> genes. Increased incidence of ZS has been suspected in French-Canadians of the Saguenay-Lac-St-Jean region (SLSJ)...