Anti-Fn14 Antibody-Conjugated Nanoparticles Display Membrane TWEAK-Like Agonism

• المؤلفون الرئيسيون: Ahmed Aido (مؤلف), Olena Zaitseva (مؤلف), Harald Wajant (مؤلف), Matej Buzgo (مؤلف), Aiva Simaite (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2021-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Conventional bivalent IgG antibodies targeting a subgroup of receptors of the TNF superfamily (TNFSF) including fibroblast growth factor-inducible 14 (anti-Fn14) typically display no or only very limited agonistic activity on their own and can only trigger receptor signaling by crosslinking or when...