Activation of AMPK Attenuated Cardiac Fibrosis by Inhibiting CDK2 via p21/p27 and miR-29 Family Pathways in Rats

• Päätekijät: Hanping Qi (Tekijä), Yan Liu (Tekijä), Shuzhi Li (Tekijä), Yunping Chen (Tekijä), Lei Li (Tekijä), Yonggang Cao (Tekijä), Mingyao E (Tekijä), Pilong Shi (Tekijä), Chao Song (Tekijä), Baiyan Li (Tekijä), Hongli Sun (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2017-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Cardiac fibrosis is pathological damage associated with nearly all forms of heart disease. AMP-activated protein kinase (AMPK) is an evolutionary conserved energy-sensing enzyme. Emerging evidences indicate that AMPK plays an important role in cardiac fibrosis and cell proliferation. However, less i...