Adverse transverse-tubule remodeling in a rat model of heart failure is attenuated with low-dose triiodothyronine treatment

• Автори: Shimin An (Автор), Nimra Gilani (Автор), Yuan Huang (Автор), Adam Muncan (Автор), Youhua Zhang (Автор), Yi-Da Tang (Автор), A. Martin Gerdes (Автор), Kaie Ojamaa (Автор)
• Формат: Книга
• Опубліковано: BMC, 2019-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Pre-clinical animal studies have shown that triiodothyronine (T3) replacement therapy improves cardiac contractile function after myocardial infarction (MI). We hypothesized that T3 treatment could prevent adverse post-infarction cardiomyocyte remodeling by maintaining transverse-tubule (TT...