Adverse transverse-tubule remodeling in a rat model of heart failure is attenuated with low-dose triiodothyronine treatment

• Egile Nagusiak: Shimin An (Egilea), Nimra Gilani (Egilea), Yuan Huang (Egilea), Adam Muncan (Egilea), Youhua Zhang (Egilea), Yi-Da Tang (Egilea), A. Martin Gerdes (Egilea), Kaie Ojamaa (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2019-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Pre-clinical animal studies have shown that triiodothyronine (T3) replacement therapy improves cardiac contractile function after myocardial infarction (MI). We hypothesized that T3 treatment could prevent adverse post-infarction cardiomyocyte remodeling by maintaining transverse-tubule (TT...