An inducible krasV12 transgenic zebrafish model for liver tumorigenesis and chemical drug screening

• Главные авторы: Anh Tuan Nguyen (Автор), Alexander Emelyanov (Автор), Chor Hui Vivien Koh (Автор), Jan M. Spitsbergen (Автор), Serguei Parinov (Автор), Zhiyuan Gong (Автор)
• Формат: ‌
• Опубликовано: The Company of Biologists, 2012-01-01T00:00:00Z.
• Предметы: article
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SUMMARY Because Ras signaling is frequently activated by major hepatocellular carcinoma etiological factors, a transgenic zebrafish constitutively expressing the krasV12 oncogene in the liver was previously generated by our laboratory. Although this model depicted and uncovered the conservation betw...