Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model

• Main Authors: Tomoki Kamatani (Author), Ryo Otsuka (Author), Tomoki Murata (Author), Haruka Wada (Author), Takeshi Takahashi (Author), Akihiro Mori (Author), Soichiro Murata (Author), Hideki Taniguchi (Author), Ken-ichiro Seino (Author)
• Format: Book
• Published: BMC, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Off-the-shelf major histocompatibility complex (MHC)-matched iPS cells (iPSC) can potentially initiate host immune responses because of the existence of numerous minor antigens. To suppress allo-immune responses, combination of immunosuppressants is usually used, but its efficacy...