Spanlastic-laden in situ gel as a promising approach for ocular delivery of Levofloxacin: In-vitro characterization, microbiological assessment, corneal permeability and in-vivo study

• Asıl Yazarlar: Omnia Ahmed Agha (Yazar), Germeen N.S. Girgis (Yazar), Mohamed M.A. El-Sokkary (Yazar), Osama Abd El-Azeem Soliman (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The objective of this study was to encapsulate the antibacterial drug levofloxacin hemihydrate (LF) into spanlastics (SLs) followed by incorporation into gelrite in situ gel to enhance its antibacterial activity and sustain ocular delivery. A combination of Span 60 as main vesicle component and Twee...