A Peptidylic Inhibitor for Neutralizing r(GGGGCC)exp-Associated Neurodegeneration in C9ALS-FTD

• Glavni autori: Qian Zhang (Autor), Ying An (Autor), Zhefan Stephen Chen (Autor), Alex Chun Koon (Autor), Kwok-Fai Lau (Autor), Jacky Chi Ki Ngo (Autor), Ho Yin Edwin Chan (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2019-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

One drug, two diseases is a rare and economical therapeutic strategy that is highly desirable in the pharmaceutical industry. We previously reported a 21-amino acid peptide named beta-structured inhibitor for neurodegenerative diseases (BIND) that can effectively inhibit expanded CAG trinucleotide t...