A Peptidylic Inhibitor for Neutralizing r(GGGGCC)exp-Associated Neurodegeneration in C9ALS-FTD

• Hoofdauteurs: Qian Zhang (Auteur), Ying An (Auteur), Zhefan Stephen Chen (Auteur), Alex Chun Koon (Auteur), Kwok-Fai Lau (Auteur), Jacky Chi Ki Ngo (Auteur), Ho Yin Edwin Chan (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2019-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

One drug, two diseases is a rare and economical therapeutic strategy that is highly desirable in the pharmaceutical industry. We previously reported a 21-amino acid peptide named beta-structured inhibitor for neurodegenerative diseases (BIND) that can effectively inhibit expanded CAG trinucleotide t...