A Peptidylic Inhibitor for Neutralizing r(GGGGCC)exp-Associated Neurodegeneration in C9ALS-FTD

• Main Authors: Qian Zhang (Author), Ying An (Author), Zhefan Stephen Chen (Author), Alex Chun Koon (Author), Kwok-Fai Lau (Author), Jacky Chi Ki Ngo (Author), Ho Yin Edwin Chan (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One drug, two diseases is a rare and economical therapeutic strategy that is highly desirable in the pharmaceutical industry. We previously reported a 21-amino acid peptide named beta-structured inhibitor for neurodegenerative diseases (BIND) that can effectively inhibit expanded CAG trinucleotide t...