The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin II

• मुख्य लेखकों: Michael Adu-Gyamfi (लेखक), Claudia Goettsch (लेखक), Julian Kamhieh-Milz (लेखक), Lei Chen (लेखक), Anna Maria Pfefferkorn (लेखक), Anja Hofmann (लेखक), Coy Brunssen (लेखक), Gregor Müller (लेखक), Thomas Walther (लेखक), Muhammad Imtiaz Ashraf (लेखक), Henning Morawietz (लेखक), Janusz Witowski (लेखक), Rusan Catar (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Endothelin-1 is a key regulator of vascular tone and blood pressure in health and disease. We have recently found that ET-1 production in human microvascular endothelial cells (HMECs) can be promoted by angiotensin II (Ang II) through a novel mechanism involving octamer-binding transcription factor-...