Screening and Evaluation of Potential Efflux Pump Inhibitors with a Seaweed Compound Diphenylmethane-Scaffold against Drug-Resistant <i>Escherichia coli</i>

• मुख्य लेखकों: Wen-Jung Lu (लेखक), Yu-Wei Lian (लेखक), Chun-Ju Chang (लेखक), Hsuan-Ju Lin (लेखक), Chian-Yun Huang (लेखक), Pang-Hung Hsu (लेखक), Hong-Ting Lin (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Drug-resistant efflux pumps play a crucial role in bacterial antibiotic resistance. In this study, potential efflux pump inhibitors (EPIs) with a diphenylmethane scaffold were screened and evaluated against drug-resistant <i>Escherichia coli</i>. Twenty-four compounds were docked against...