Screening and Evaluation of Potential Efflux Pump Inhibitors with a Seaweed Compound Diphenylmethane-Scaffold against Drug-Resistant <i>Escherichia coli</i>

• Glavni autori: Wen-Jung Lu (Autor), Yu-Wei Lian (Autor), Chun-Ju Chang (Autor), Hsuan-Ju Lin (Autor), Chian-Yun Huang (Autor), Pang-Hung Hsu (Autor), Hong-Ting Lin (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2024-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Drug-resistant efflux pumps play a crucial role in bacterial antibiotic resistance. In this study, potential efflux pump inhibitors (EPIs) with a diphenylmethane scaffold were screened and evaluated against drug-resistant <i>Escherichia coli</i>. Twenty-four compounds were docked against...