Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency

Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency

Mitochondrial disorders represent a heterogeneous group of genetic disorders with variations in severity and clinical outcomes, mostly characterized by respiratory chain dysfunction and abnormal mitochondrial function. More specifically, mutations in the human <i>SCO2</i> gene, encoding...

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Main Authors: Androulla N. Miliotou (Author), Parthena F. Foltopoulou (Author), Alexandra Ingendoh-Tsakmakidis (Author), Asterios S. Tsiftsoglou (Author), Ioannis S. Vizirianakis (Author), Ioannis S. Pappas (Author), Lefkothea C. Papadopoulou (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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