Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency

• Asıl Yazarlar: Androulla N. Miliotou (Yazar), Parthena F. Foltopoulou (Yazar), Alexandra Ingendoh-Tsakmakidis (Yazar), Asterios S. Tsiftsoglou (Yazar), Ioannis S. Vizirianakis (Yazar), Ioannis S. Pappas (Yazar), Lefkothea C. Papadopoulou (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Mitochondrial disorders represent a heterogeneous group of genetic disorders with variations in severity and clinical outcomes, mostly characterized by respiratory chain dysfunction and abnormal mitochondrial function. More specifically, mutations in the human <i>SCO2</i> gene, encoding...