Glomerular injury induced by vinyl carbamate in A/J inbred mice: a novel model of membranoproliferative glomerulonephritis

• Main Authors: Athena Y. Gong (Author), Ying Jin Qiao (Author), Mengxuan Chen (Author), Zubia Alam (Author), Deepak K. Malhotra (Author), Lance Dworkin (Author), Wenjun Ju (Author), William T. Gunning (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ethyl carbamate (EC) is a process contaminant found in fermented foods and alcoholic beverages. Metabolic conversion of ethyl carbamate generates vinyl carbamate (VC), a carcinogenic metabolite. EC, as a Group 2A probable human carcinogen, and the more potent VC, are known to cause tumors in rodents...