Glomerular injury induced by vinyl carbamate in A/J inbred mice: a novel model of membranoproliferative glomerulonephritis

• Autori principali: Athena Y. Gong (Autore), Ying Jin Qiao (Autore), Mengxuan Chen (Autore), Zubia Alam (Autore), Deepak K. Malhotra (Autore), Lance Dworkin (Autore), Wenjun Ju (Autore), William T. Gunning (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Ethyl carbamate (EC) is a process contaminant found in fermented foods and alcoholic beverages. Metabolic conversion of ethyl carbamate generates vinyl carbamate (VC), a carcinogenic metabolite. EC, as a Group 2A probable human carcinogen, and the more potent VC, are known to cause tumors in rodents...